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CAS No.: 686770-61-6
Synonyms: Inhibitor of Wnt Production-2
IWP-2 is an inhibitor of porcn-mediated Wnt palmitoylation and secretion with IC50 of 27 nM.
生物活性
靶点 | Wnt IC50:27nM |
实验方案
技术信息
CAS号 | 686770-61-6 | 储存条件 |
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分子式 | C22H18N4O2S3 | 运输 | 蓝冰 | |||||||||||||||
分子量 | 466.60 | 别名 | Inhibitor of Wnt Production-2 | |||||||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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mouse L cells | - | Function assay | 24 h | Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay, EC50=30 nM | 23477365 |
靶点 | Description | IC50 |
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Wnt | IC50:27nM |
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